Endocrine Abstracts

Purpose: To determine the association between clinical indicators of metabolic state and cardiovascular, infectious and metabolic complications during or after elective surgery in patients with type 2 diabetes mellitus (T2DM) regardless of their treatment scheme.Methods: Prospective observational study. Patients with T2DM, ages 20–80 years, scheduled for elective surgery were evaluated with office BP, BMI, Hb1Ac, fasting glucose, fibrinogen, total c...

Introduction: Non-functioning pituitary tumors and primary empty sella are a common pathology within the differential diagnosis of pituitary masses. The manifestations will depend on the size of the tumor and the compression of adjacent structures being the most frequent neurological symptoms. Clinically the two entities are very similar and no clinical tools are known to be able to help the differential diagnosis.Objective: Perform a clinical and compar...

Background: Orolactin-producing tumours are the most frequent pituitary tumours, representing 40% of these tumours, with an annual incidence of 6–10 cases/million. <10% are macroprolactinomas, which vary by age and gender, with female to male ratio of 10:1, however, less diagnosed in this population group.Objective: To describe clinical features and therapeutic response of 30 women with invasive macroprolactinoma.Methods: ...

To describe the course of acromegaly in a group of seven women, before, during, and after pregnancy.Methods: Descriptive case series of acromegalic pregnant women attending a reference health center in Cali, Colombia.Results: Mean age at conception was 29±10 years, starting prenatal care at 10±3 weeks of gestation. 6 of 7 patients had a macroadenoma as evidenced by neuroimaging (MRI). 43% (three cases) had GH and prolacti...

Introduction: Prolactin-producing pituitary adenomas are the most common pituitary tumors in clinical practice. In men they are more aggressive and their response to pharmacological treatment is unknown.Objective: Describe the clinical characteristics and response according to the treatment of a group of male patients with invasive macroprolactinomas.Materials and methods: A retrospective descriptive study, a series of cases, in 30...

Background and aims: To describe the characteristics of patients with non-controlled type 2 diabetes mellitus with liraglutide treatment.Materials and methods: Retrospective descriptive study. 85 outpatients (women 49, ages 18–86 years old with non-controlled type 2 diabetes mellitus were evaluated between July 2013 and March 2014 and received treatment with liraglutide 1.8 mg Q18/day (0.6 mg Q18 during the first week, 1.2 mg Q18 during the send wee...

Background and aims: To describe the characteristics of patients with non-controlled type 2 diabetes mellitus with liraglutide treatment.Materials and methods: Retrospective descriptive study. 85 outpatients (women 49, ages 18–86 years old with non-controlled type 2 diabetes mellitus) were evaluated between July 2013 and March 2014 and received treatment with liraglutide 1.8 mg SQ/day (0.6 mg SQ during the first week, 1.2 mg SQ during the second wee...

Introduction: Rituximab is indicated in patients with active rheumatoid arthritis (RA), which through the Fab domain, binds to the CD20 antigen on the surface of B lymphocytes, generating lysis of B cells, present in the thyroid, by cytotoxicity dependent on complement, as a result of the binding of C1q, mediated by the Fc domain, destroying the thyroid follicles, by infiltration of inflammatory cells (1) (2).Objective: Describe the characteristics of pa...

Hyperthyroidism during pregnancy is determined by decreased thyroid stimulating hormone (TSH), and high levels of thyroid hormones: thyroxine (T4), triiodothyronine (T3), being a complication in 1–2 women per 1,000 pregnancies, and occurs first as Graves’ disease in 0.1–1% of pregnancies. There are specific reference ranges of THS and free T4 for each population and each trimester. For the medical management in the first trimeste...

Introduction: Non-classic congenital adrenal hyperplasia (NCCAH) is an autosomal recessive disorder, that affects adrenal steroidogenesis, and it is characterized by an enzymatic defect in corticosteroids biosynthesis. NCCAH diagnosis is based on the determination of 17a-hydroxiprogesterone (17a-OHP) basal levels, and levels after stimulation with adrenocorticotropic hormone (ACTH), and it is confirmed with molecular testing. Treatment is still controversial, and it must be in...